Journal of Clinical and Experimental Investigations

Abstract

Objective: Ovarian cancers, the relatively high frequency, poor prognosis and late diagnosis are considerable clinical issues and additional diagnostic methods are needed. The aim of this study was to evaluate the predictive value of RMI as a diagnostic marker in ovarian cancers.
Methods: Totally 80 patients with adnexal masses who were operated in Haydarpaşa Numune Training and Research Hospital Gynecology and Obstetrics Department between January 2012-June 2012, included in the study. This was a retrospective observational study. All patient’ documents were reevaluated and calculated for RMI. The calculated results were compared with histopathologic findings.
Results: The 30% (n=24) of women were in postmenopousal period. The major complains of patients during attendance were pelvic pain (65%) and 27.5% of the patients had no complaints and adnexal masses were detected during routine gynecological examination The 86.3% (n=69) of women had benign ovarian neoplasms, 11.3% (n=9) had malignant tumors and 2.5% (n=2) had borderline ovarian tumors. Most of the women with high RMI levels were in postmenopousal status (71.5%). The sensitivity and specificity of RMI were 81.8% and 92.6% respectively. The sensitivity and specificity of CA-125 levels were 90.9% and 36.4% respectively.
Conclusion: Using RMI in diagnosis of malign ovarian tumors is easily appliable method with high sensitivity and specificity without financial burden.