Journal of Clinical and Experimental Investigations

Abstract

Objective: Urinary tract infections (UTI) come upon a common infection disease in hospital. Empiric antibiotic therapy for patients with suspected UTI is commonly used because obtaining antibiogram result is usually time consuming. Aim of the study was to investigate urine culture and antibiogram results of patients who were admitted to our hospital.
Methods: Urine cultures were investigated between November 2008 and June 2010 in database of laboratory information system. Samples of isolated microorganism and antibiogram results were evaluated.
Results: Microorganisms were isolated in 691 of 1342 urine cultures. Polymicrobial infection was determined in 46 patients. Most common identified microorganism was E. coli (71.3%). If all samples considered, bacteria resistance was detected against to ampicilline, trimethoprim/sulfamethoxazole (TMP/SMX) ampicilline/sulbactam (AMS) and ciprofloxacin (CIP) (52.1%, 39.5%, 22.7% and 19.6%). Lower bacterial resistance was determined against amicasin, gentamicine, tobramicine and nitrofurantoin (7.9%, 3.3%, 17.5% and 12.6%). As E. coli isolated samples were investigated, bacterial resistance was detected against ampicilline, CIP, levofloxacin and TMP/SMX (58.1%, 40.8%, 36.1% ve 39.5%). Nitrofurantoin, amicasin, gentamicine and tobramicine were found as sensitive antibiotics (90.3%, 88.9%, 79.4% and 69.9%).
Conclusion: High bacterial resistance was determined against to most preferred empiric antibiotics which are TMP/SMX, AMS and also CIP.