Journal of Clinical and Experimental Investigations

Abstract

Objectives: Acute necrotizing pancreatitis is a condition still with high morbidity and mortality which is associated with severe acute pancreatitis because parenchyma necrosis occurs during illness. Our aim in this study is to examine the factors affecting mortality in patients undergoing surgery because of acute necrotizing pancreatitis and present our surgical outcomes.
Materials and methods: The clinical features, Ranson and APACHE II scores of 38 patients operated in clinic (2006-2012) for acute necrotizing pancreatitis were recorded retrospectively.
Results: From the patients included in the study, 11 (28.9%) were male and 27 (71.1%) were female with an age average of 55.1±16.0 years. No relationship was found between age, C-reactive proteins, amylase and liver enzymes, pancreatitis etiology, complications seen after surgery and mortality (p>0.05). The effects of white blood cell values, width of necrosis area and the APACHE II and Ranson values upon admission on mortality were significant (p<0.05).
Conclusions: Acute necrotizing pancreatitis is a disease difficult to treat with mortality rates remaining high. In our study we determined that the patients' white blood cellcounts, Ranson values, APACHE II scores and necrosis width had negative effects on mortality. If the patient cannot be stabilized or there are indications required for the surgery, surgery must be planned as soon as the patient is suitable for operation.