Pathogenesis, Diagnosis and Possible Therapeutic Options for COVID-19
Md. Asad Ullah 1 * , Yusha Araf 2, Bishajit Sarkar 1, Abu Tayab Moin 3, Riyan Al Islam Reshad 2, MD. Hasanur Rahman 4
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1 Department of Biotechnology and Genetic Engineering, Faculty of Biological Sciences, Jahangirnagar University, Dhaka, Bangladesh2 Department of Genetic Engineering and Biotechnology, School of Life Sciences, Shahjalal University of Science and Technology, Sylhet, Bangladesh3 Department of Genetic Engineering and Biotechnology, School of Life Sciences, University of Chittagong, Chottogram, Bangladesh4 Department of Biotechnology and Genetic Engineering, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Faculty of Life Sciences, Gopalganj, Bangladesh* Corresponding Author

Abstract

The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread so rapidly and severely affected the people of almost every country in the world. The highly contagious nature of this virus makes it difficult to take control of the present pandemic situation. With no specific treatment available, the coronavirus disease 2019 (COVID-19) presents a threat to people of all ages including the elderly people and people with other medical complications as a vulnerable group to this disease. Better understanding of viral pathogenesis, appropriate preventive measures, early diagnosis and supportive treatments of the infected patients are now the general solutions to fight against this viral transmission. But, as an emerging disease, most about it remains still poorly understood. This article holds an overview on the origin and structure, pathogenesis, diagnosis and possible therapeutic options for the causative agent, SARS-CoV-2 and disease, COVID-19. However, few therapeutic options, laboratory experiments and other strategies proposed here need to be further clinically tested.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

J Clin Exp Invest, Volume 11, Issue 4, December 2020, Article No: em00755

https://doi.org/10.29333/jcei/8564

Publication date: 07 Oct 2020

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Article Downloads: 939

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